1309976-66-6
1309976-66-6
Chemical Structure
VU0361747
- CAS. Nr.: 1309976-66-6
- Formula:C19H17FN2O2
- Molecular Weight:324.35
IUPAC Name: (6-((3-fluorophenyl)ethynyl)pyridin-3-yl)(4-hydroxypiperidin-1-yl)methanone
InChIKey: ZKKOJUZGUBLAJQ-UHFFFAOYSA-N
SMILES: OC1CCN(CC1)C(C2=CC=C(N=C2)C#CC3=CC=CC(F)=C3)=O
Biological Activity: VU0361747 is a potent and selective positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4 PAM). VU0361737 has neuroprotective effect. VU0361737 significantly reverses Amphetamine-induced hyperlocomotion in vivo[1].
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VU0361747 | VU0361747 is a potent and selective positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4 PAM). VU0361737 has neuroprotective effect. VU0361737 significantly reverses Amphetamine-induced hyperlocomotion in vivo. | |||||||||||||||||||||
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