1334492-85-1
Chemical Structure
BP-1-108
- CAS No.: 1334492-85-1
- Formula:C32H38N2O6S
- Molecular Weight:578.72
IUPAC Name: 4-(N-(4-cyclohexylbenzyl)-2-((N,2,4,6-tetramethylphenyl)sulfonamido)acetamido)-2-hydroxybenzoic acid
InChIKey: XRIZHIWNZHWNQG-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(C)S(=O)(C4=C(C)C=C(C)C=C4C)=O)=O)C=C1O
Biological Activity: BP-1-108 is a selective inhibitor of STAT5 (Ki=8.3 μM) with anticancer activity. BP-1-108 induces apoptosis of leukemia cells by inhibiting the phosphorylation of STAT5. BP-1-108 can be used in the study of acute myeloid leukemia and prostate cancer[1].
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BP-1-108 | BP-1-108 is a selective inhibitor of STAT5 (Ki=8.3 μM) with anticancer activity. BP-1-108 induces apoptosis of leukemia cells by inhibiting the phosphorylation of STAT5. BP-1-108 can be used in the study of acute myeloid leukemia and prostate cancer. | |||||||||||||||||||||
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Keywords
