1338824-20-6
1338824-20-6
Chemical Structure
NCGC00229600
- CAS No.: 1338824-20-6
- Formula:C30H29N3O3
- Molecular Weight:479.57
IUPAC Name: 2-(3-((2,6-dimethylphenoxy)methyl)-4-methoxyphenyl)-3-(pyridin-3-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one
InChIKey: ODFGSMOTQLYMHU-UHFFFAOYSA-N
SMILES: O=C1N(CC2=CC=CN=C2)C(C3=CC=C(OC)C(COC4=C(C)C=CC=C4C)=C3)NC5=C1C=CC=C5
Biological Activity: NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease[1].
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NCGC00229600 | 99.67% | NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease. | ||||||||||||||||||||
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References
Keywords
