1. GPCR/G Protein
  2. TSH Receptor
  3. NCGC00229600

NCGC00229600 

Cat. No.: HY-18286
Handling Instructions

NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease.

For research use only. We do not sell to patients.

NCGC00229600 Chemical Structure

NCGC00229600 Chemical Structure

CAS No. : 1338824-20-6

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Description

NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease[1].

Molecular Weight

479.57

Formula

C₃₀H₂₉N₃O₃

CAS No.

1338824-20-6

SMILES

O=C1N(CC2=CC=CN=C2)C(C3=CC=C(OC)C(COC4=C(C)C=CC=C4C)=C3)NC5=C1C=CC=C5

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

NCGC00229600NCGC 00229600NCGC-00229600TSH ReceptorThyrotropin receptorThyroid-stimulating hormone ReceptorfibroblastsGravesdiseasecAMP antibodyendogenouslyInhibitorinhibitorinhibit

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NCGC00229600
Cat. No.:
HY-18286
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