134031-86-0
Chemical Structure
3'-O-DMTr-thymidine 5'-CE phosphoramidite
- CAS No.: 134031-86-0
- Formula:C40H49N4O8P
- Molecular Weight:744.81
IUPAC Name: ((2R,3S,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: PYRVCWBKTIQJDJ-CEXSRUIHSA-N
SMILES: O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](COP(OCCC#N)N(C(C)C)C(C)C)[C@@H](OC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5)C2
Biological Activity: 3’-O-DMTr-thymidine 5’-CE phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3'-O-DMTr-thymidine 5'-CE phosphoramidite | 3’-O-DMTr-thymidine 5’-CE phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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