1346598-64-8
1346598-64-8
Chemical Structure
2-Benzothiazolethiol-d4
- CAS No.: 1346598-64-8
- Formula:C7HD4NS2
- Molecular Weight:171.28
IUPAC Name: benzo[d]thiazole-2(3H)-thione-4,5,6,7-d4
InChIKey: YXIWHUQXZSMYRE-RHQRLBAQSA-N
SMILES: S=C1NC(C([2H])=C(C([2H])=C2[2H])[2H])=C2S1
Biological Activity: 2-Benzothiazolethiol-d4 is the deuterium labeled 2-Benzothiazolethiol-d4 (HY-W653751)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Benzothiazolethiol-d4 | 99.74% | 2-Benzothiazolethiol-d4 is the deuterium labeled 2-Benzothiazolethiol-d4 (HY-W653751). | ||||||||||||||||||||
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2-Mercaptobenzothiazole (Standard) | ≥98% | 2-Mercaptobenzothiazole (Standard) is the analytical standard of 2-Mercaptobenzothiazole. This product is intended for research and analytical applications. 2-Mercaptobenzothiazole is an endogenous metabolite. | ||||||||||||||||||||
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2-Mercaptobenzothiazole | 99.49% | 2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR), inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity. 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1. 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC50 value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis. 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats. 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes. | ||||||||||||||||||||
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References
