1346605-01-3
1346605-01-3
Chemical Structure
(±)-Penbutolol-d9 hydrochloride
Synonym(s): (Rac)-Penbutolol-d9 hydrochloride; (±)-Isopenbutolol-d9 hydrochloride
- CAS No.: 1346605-01-3
- Formula:C18H21D9ClNO2
- Molecular Weight:336.94
IUPAC Name: 1-(2-cyclopentylphenoxy)-3-((2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)amino)propan-2-ol hydrochloride
InChIKey: ITZWQFLTSRCDPC-KYRNGWDOSA-N
SMILES: OC(CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])COC1=CC=CC=C1C2CCCC2.[H]Cl
Biological Activity: (±)-Penbutolol-d9 (hydrochloride) is a deuterium labeled (±)-Penbutolol hydrochloride. (+)-Penbutolol hydrochloride is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(±)-Penbutolol-d9 hydrochloride | (±)-Penbutolol-d9 (hydrochloride) is a deuterium labeled (±)-Penbutolol hydrochloride. (+)-Penbutolol hydrochloride is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(±)-Penbutolol-d9 | (±)-Penbutolol-d9 is the deuterium labeled (±)-Penbutolol. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(±)-Penbutolol | 98.07% | (±)-Penbutolol ((Rac)-Penbutolol) is the racemic mixture of Penbutolol. (±)-Penbutolol is an orally active β-adrenergic receptor antagonist. (±)-Penbutolol antagonizes exercise-induced tachycardia, reduces the increase in peak expiratory flow rate (PEFR) caused by exercise, and decreases resting plasma renin activity (PRA). (±)-Penbutolol reaches peak plasma concentration 1 hour after oral administration, with a half-life of 4.5 hours, and is converted into an active metabolite in the body. (±)-Penbutolol can be used in cardiovascular-related disease research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
