1350752-07-6
Chemical Structure
G9a-IN-1
- CAS No.: 1350752-07-6
- Formula:C24H36ClN5O2
- Molecular Weight:462.03
IUPAC Name: 2-chloro-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
InChIKey: GHTIAKXLWWMKSI-UHFFFAOYSA-N
SMILES: CC(N1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(Cl)=N2)CC1)C
Biological Activity: G9a-IN-1 (Compound 113) is a G9a protein inhibitor. G9A/EHMT2 is a nuclear histone lysine methyltransferase that catalyzes histone H3 lysine 9 dimethylation (H3K9me2), which is a reversible modification generally associated with transcriptional gene silencing. G9a-IN-1 can be used for the research of autoimmune disorders or cancer[1].
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G9a-IN-1 | 98.12% | G9a-IN-1 (Compound 113) is a G9a protein inhibitor. G9A/EHMT2 is a nuclear histone lysine methyltransferase that catalyzes histone H3 lysine 9 dimethylation (H3K9me2), which is a reversible modification generally associated with transcriptional gene silencing. G9a-IN-1 can be used for the research of autoimmune disorders or cancer. | ||||||||||||||||||||
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Keywords
