135124-72-0
Chemical Structure
AY 31390
- CAS No.: 135124-72-0
- Formula:C11H11Br3N4O
- Molecular Weight:454.94
IUPAC Name: 5-bromo-6-(((5-bromopyridin-3-yl)methyl)amino)-2-methylpyrimidin-4(1H)-one hydrobromide
InChIKey: BDODSLWDJUXYCQ-UHFFFAOYSA-N
SMILES: O=C1N=C(C)NC(NCC2=CC(Br)=CN=C2)=C1Br.Br
Biological Activity: AY 31390 is a potent PDE III inhibitor. AY 31390 increases intracellular cAMP levels by selectively inhibiting the low-Km cAMP-specific PDE III, thereby stabilizing platelets and exerting antithrombotic effects independently of plasma adenosine concentrations. AY 31390 can be used in the study of thrombosis, angina pectoris, cerebral ischemia, and peripheral vascular diseases[1].
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AY 31390 | AY 31390 is a potent PDE III inhibitor. AY 31390 increases intracellular cAMP levels by selectively inhibiting the low-Km cAMP-specific PDE III, thereby stabilizing platelets and exerting antithrombotic effects independently of plasma adenosine concentrations. AY 31390 can be used in the study of thrombosis, angina pectoris, cerebral ischemia, and peripheral vascular diseases. | |||||||||||||||||||||
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