135472-91-2
135472-91-2
Chemical Structure
Selenotifen
Synonym(s): BN 52256
- No. CAS: 135472-91-2
- Formula:C19H19NOSe
- Molecular Weight:356.32
IUPAC Name: 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]selenophen-10-one
InChIKey: VRLFMTNYDWKTEJ-UHFFFAOYSA-N
SMILES: O=C1C2=C(/C(C3=C(C1)C=CC=C3)=C4CCN(CC\4)C)C=C[Se]2
Biological Activity: Selenotifen (BN 52256) is an antiallergic agent. Selenotifen is a highly potent antagonist to PAF receptors. Selenotifen exhibits a statistically significant antiarrhythmic effect[1][2].
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Selenotifen | Selenotifen (BN 52256) is an antiallergic agent. Selenotifen is a highly potent antagonist to PAF receptors. Selenotifen exhibits a statistically significant antiarrhythmic effect. | |||||||||||||||||||||
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References
- [1]. May SW, et al. Selenium-based antihypertensives. Rationale and potential. Drugs. 1998 Dec;56(6):959-64. [Content Brief]
- [2]. Mest HJ, et al. Effect of BN 52256 and other mediator antagonists on ouabain-induced cardiac arrhythmia in a model of anaphylaxis in guinea-pigs. Pharmacol Res. 1992 Feb-Mar;25(2):173-80. [Content Brief]
