1356154-94-3
1356154-94-3
Chemical Structure
PND-1186 hydrochloride
Synonym(s): VS-4718 hydrochloride; SR-2516 hydrochloride
- CAS No.: 1356154-94-3
- Formula:C25H27ClF3N5O3
- Molecular Weight:537.96
IUPAC Name: 2-((2-((2-methoxy-4-morpholinophenyl)amino)-5-(trifluoromethyl)pyridin-4-yl)amino)-N-methylbenzamide hydrochloride
InChIKey: OWQFAUOQRRIFLB-UHFFFAOYSA-N
SMILES: [H]Cl.O=C(NC)C1=CC=CC=C1NC2=CC(NC3=CC=C(N4CCOCC4)C=C3OC)=NC=C2C(F)(F)F
Biological Activity: PND-1186 hydrochloride (VS-4718 hydrochloride) is a potent, highly-specific and reversible inhibitor of FAK with an IC50 of 1.5 nM. PND-1186 hydrochloride selectively promotes tumor cell apoptosis[1].
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PND-1186 hydrochloride | 99.92% | PND-1186 hydrochloride (VS-4718 hydrochloride) is a potent, highly-specific and reversible inhibitor of FAK with an IC50 of 1.5 nM. PND-1186 hydrochloride selectively promotes tumor cell apoptosis. | ||||||||||||||||||||
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