1356409-07-8
Chemical Structure
2-Phenyl-1-octen-7-yn-1-one
- CAS No.: 1356409-07-8
- Formula:C14H14O
- Molecular Weight:198.27
IUPAC Name: 2-phenyloct-1-en-7-yn-1-one
InChIKey: GHOFJUGLQQHQDG-UHFFFAOYSA-N
SMILES: O=C=C(C=1C=CC=CC1)CCCCC#C
Biological Activity: 2-Phenyl-1-octen-7-yn-1-one is an alkyne-functionalized enone with site-selective reactivity toward the N-terminal α-amino group of peptides and proteins. 2-Phenyl-1-octen-7-yn-1-one can undergo click chemistry with azides via its alkyne moiety to enable further protein functionalization. 2-Phenyl-1-octen-7-yn-1-one modifies unprotected peptide libraries as well as proteins including insulin, lysozyme, RNaseA and BCArg[1].
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2-Phenyl-1-octen-7-yn-1-one | 2-Phenyl-1-octen-7-yn-1-one is an alkyne-functionalized enone with site-selective reactivity toward the N-terminal α-amino group of peptides and proteins. 2-Phenyl-1-octen-7-yn-1-one can undergo click chemistry with azides via its alkyne moiety to enable further protein functionalization. 2-Phenyl-1-octen-7-yn-1-one modifies unprotected peptide libraries as well as proteins including insulin, lysozyme, RNaseA and BCArg. | |||||||||||||||||||||
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Keywords