1357252-79-9
1357252-79-9
Chemical Structure
Silodosin carboxylic acid impurity
Synonym(s): KMD-3293
- CAS No.: 1357252-79-9
- Formula:C25H30F3N3O5
- Molecular Weight:509.52
InChIKey: VIWKOELUJFEJEQ-MRXNPFEDSA-N
SMILES: OC(CCN1C2=C(C(N)=O)C=C(C[C@@H](C)NCCOC3=C(C=CC=C3)OCC(F)(F)F)C=C2CC1)=O
Biological Activity: Silodosin carboxylic acid impurity (KMD-3293) is an inactive silodosin metabolite. Silodosin carboxylic acid impurity is the major metabolite that can be generated via oxidation by alcohol and aldehyde dehydrogenase. Silodosin carboxylic acid impurity can be studied in research for benign prostatic hyperplasia[1][2].
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Silodosin carboxylic acid impurity | Silodosin carboxylic acid impurity (KMD-3293) is an inactive silodosin metabolite. Silodosin carboxylic acid impurity is the major metabolite that can be generated via oxidation by alcohol and aldehyde dehydrogenase. Silodosin carboxylic acid impurity can be studied in research for benign prostatic hyperplasia. | |||||||||||||||||||||
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References
- [1]. Shah, P. A., & Shrivastav, P. S. (2018). Novel LC-MS/MS method for the quantification of silodosin and its metabolites in human plasma. Bioanalysis, 10(1), 7–10. [Content Brief]
- [2]. Lepor, H., & Hill, L. A. (2010). Silodosin for the treatment of benign prostatic hyperplasia: pharmacology and cardiovascular tolerability. Pharmacotherapy, 30(12), 1303–1312. [Content Brief]
Keywords
