1357578-02-9
Chemical Structure
BD-Oligo
- CAS 番号: 1357578-02-9
- Formula:C25H24BCl3F2N2O4
- Molecular Weight:571.64
InChIKey: LTYJVBBHDBFIQG-BQYQJAHWSA-N
SMILES: OC(C(OCC)=CC=C1)=C1/C=C/C2=[N]3C(C(C)=C2)=CC4=CC=C(CCC(OCC(Cl)(Cl)Cl)=O)[N-]4[B+3]3([F-])[F-]
Biological Activity: BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo[1].
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BD-Oligo | 98.18% | BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo. | ||||||||||||||||||||
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