1359087-83-4
1359087-83-4
Chemical Structure
VU0415248
- CAS No.: 1359087-83-4
- Formula:C21H23N5O3S
- Molecular Weight:425.50
InChIKey: KZEVRYRKBGRMEZ-UHFFFAOYSA-N
SMILES: O=C(CCNS(=O)(C1=CC=CC2=NC=CC=C21)=O)N3CCN(CC3)C4=CC=NC=C4
Biological Activity: VU0415248 is a selective muscarinic acetylcholine receptor 1 (M1) inhibitor. VU0415248 inhibits acetylcholine-induced calcium mobilization in cells expressing human and rat M1 muscarinic acetylcholine receptors, with an IC50 of 0.4 and 0.18 μM, respectively. VU0415248 is applicable to the research of Parkinson's disease, movement disorders and fragile X syndrome[1].
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VU0415248 | VU0415248 is a selective muscarinic acetylcholine receptor 1 (M1) inhibitor. VU0415248 inhibits acetylcholine-induced calcium mobilization in cells expressing human and rat M1 muscarinic acetylcholine receptors, with an IC50 of 0.4 and 0.18 μM, respectively. VU0415248 is applicable to the research of Parkinson's disease, movement disorders and fragile X syndrome. | |||||||||||||||||||||
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References
Keywords
