1370651-20-9
1370651-20-9
Chemical Structure
Ensartinib
Synonym(s): X-396
- CAS No.: 1370651-20-9
- Formula:C26H27Cl2FN6O3
- Molecular Weight:561.44
IUPAC Name: 6-amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-N-(4-((3R,5S)-3,5-dimethylpiperazine-1-carbonyl)phenyl)pyridazine-3-carboxamide
InChIKey: GLYMPHUVMRFTFV-QLFBSQMISA-N
SMILES: O=C(C1=NN=C(N)C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)=C1)NC3=CC=C(C(N4C[C@@H](C)N[C@@H](C)C4)=O)C=C3
Biological Activity: Ensartinib (X-396) is a BBB-permeable and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Ensartinib | 99.93% | Ensartinib (X-396) is a BBB-permeable and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. | ||||||||||||||||||||
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