13756-49-5
13756-49-5
Chemical Structure
3,4,3'-Tri-O-methylflavellagic acid
- CAS No.: 13756-49-5
- Formula:C17H12O9
- Molecular Weight:360.27
InChIKey: BLICLJSLKJVPKA-UHFFFAOYSA-N
SMILES: O=C1OC(C(OC)=C(C(O)=C23)OC)=C3C4=C1C=C(O)C(OC)=C4OC2=O
Biological Activity: 3,4,3'-Tri-O-methylflavellagic acid is a flavonoid inhibitor that targets αβ-tubulin (colchicine binding site) and polo-like kinase-1 (PLK-1), and can be isolated from the roots of Anogeissus leiocarpus. 3,4,3'-Tri-O-methylflavellagic acid interferes with microtubule assembly dynamics and kinase activity, exhibiting anti-cancer cell proliferation and potent anti-nociceptive effects[1].
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3,4,3'-Tri-O-methylflavellagic acid | 3,4,3'-Tri-O-methylflavellagic acid is a flavonoid inhibitor that targets αβ-tubulin (colchicine binding site) and polo-like kinase-1 (PLK-1), and can be isolated from the roots of Anogeissus leiocarpus. 3,4,3'-Tri-O-methylflavellagic acid interferes with microtubule assembly dynamics and kinase activity, exhibiting anti-cancer cell proliferation and potent anti-nociceptive effects. | |||||||||||||||||||||
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Keywords
