137563-64-5
137563-64-5
Chemical Structure
Eurystatin B
- CAS No.: 137563-64-5
- Formula:C24H40N4O5
- Molecular Weight:464.60
InChIKey: YNIGBMUXBCZRNQ-XYOKQWHBSA-N
SMILES: O=C(N[C@@H]1C(N[C@@H](C)C(C(N[C@@H](CC(C)C)C(NCCC1)=O)=O)=O)=O)/C=C/CCC(CC)C
Biological Activity: Eurystatin B is a prolyl endopeptidase (PED) inhibitor. Eurystatin B has a protective effect during Scopolamine (HY-N0296)-induced amnesia in rats[1][2].
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Eurystatin B | Eurystatin B is a prolyl endopeptidase (PED) inhibitor. Eurystatin B has a protective effect during Scopolamine (HY-N0296)-induced amnesia in rats. | |||||||||||||||||||||
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References
- [1]. Suzuki K, et al. Eurystatins A and B, new prolyl endopeptidase inhibitors. III. Fermentation and controlled biosynthesis of eurystatin analogs by Streptomyces eurythermus. J Antibiot (Tokyo). 1994 Sep;47(9):982-91. [Content Brief]
- [2]. Kamei H, et al. Protective effect of eurystatins A and B, new prolyl endopeptidase inhibitors, on scopolamine-induced amnesia in rats. Jpn J Pharmacol. 1992 Dec;60(4):377-80. [Content Brief]
Keywords
