1377272-66-6
1377272-66-6
Chemical Structure
MRS5663
- CAS No.: 1377272-66-6
- Formula:C22H21ClN6O3
- Molecular Weight:452.89
InChIKey: HYTZGNCPPKEQEP-YWNJHDJRSA-N
SMILES: CNC1=NC(C#CC2=CC=CC=C2Cl)=NC3=C1N=CN3[C@@H]4[C@@H](C5)[C@]5(C(NC)=O)[C@@H](O)[C@H]4O
Biological Activity: MRS5663 (Compound 3a) is an A3AR agonist, with an EC50 of 5.62 nM for β-arrestin2 recruitment assay. MRS5663 has a cytoprotective effect on skeletal muscle ischemia-reperfusion injury/claudication model[1].
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MRS5663 | MRS5663 (Compound 3a) is an A3AR agonist, with an EC50 of 5.62 nM for β-arrestin2 recruitment assay. MRS5663 has a cytoprotective effect on skeletal muscle ischemia-reperfusion injury/claudication model. | |||||||||||||||||||||
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