1379573-88-2
1379573-88-2
Chemical Structure
CBB1003
- CAS No.: 1379573-88-2
- Formula:C25H31N9O4
- Molecular Weight:521.57
IUPAC Name: 4-(3-(4-(4-carbamimidoylbenzoyl)piperazine-1-carbonyl)-5-nitrobenzyl)piperazine-1-carboximidamide
InChIKey: SKTVJNLOILHEKO-UHFFFAOYSA-N
SMILES: NC(N1CCN(CC2=CC(C(N3CCN(C(C4=CC=C(C(N)=N)C=C4)=O)CC3)=O)=CC([N+]([O-])=O)=C2)CC1)=N
Biological Activity:
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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CBB1003 | CBB1003 is a novel histone demethylase LSD1 inhibitor with IC50 of 10. | |||||||||||||||||||||
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References
- Wang J, et al. Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties. Cancer Res. 2011 Dec 1;71(23):7238-49. [Content Brief]
- Hsu HC, et al. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol. 2014 Jul 25. [Content Brief]
Keywords
