1386980-55-7
Chemical Structure
DYRKs-IN-1 hydrochloride
- CAS No.: 1386980-55-7
- Formula:C30H31Cl2N7O4
- Molecular Weight:624.52
IUPAC Name: N-(5-((3-amino-1-phenylpropyl)carbamoyl)-2-chlorophenyl)-2-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide hydrochloride
InChIKey: XLHHYTUBPOMTDK-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CN=C(N3CC(O4)CCC4C3)N=C2NC1=O)NC5=CC(C(NC(C6=CC=CC=C6)CCN)=O)=CC=C5Cl.[H]Cl
Biological Activity: DYRKs-IN-1 hydrochloride is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. DYRKs-IN-1 hydrochloride has antitumor activity[1][2].
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DYRKs-IN-1 hydrochloride | 98.29% | DYRKs-IN-1 hydrochloride is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. DYRKs-IN-1 hydrochloride has antitumor activity. | ||||||||||||||||||||
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Keywords
