1392-21-8
1392-21-8
Chemical Structure
Leucomycin
Synonym(s): Kitasamycin
- CAS No.: 1392-21-8
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Leucomycin]
Biological Activity: Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses[1][2][3][4][5][6][7].
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Leucomycin | Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses. | |||||||||||||||||||||
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References
- [1]. PACHTMAN EA, et al. Leucomycin; a new antibiotic. Am J Pharm Sci Support Public Health. 1958 Oct;130(10):342-4. [Content Brief]
- [2]. Vézina C, et al. Biosynthesis of kitasamycin (leucomycin) by leucine analog-resistant mutants of Streptomyces kitasatoensis. Antimicrob Agents Chemother. 1979 May;15(5):738-46. [Content Brief]
- [3]. La T, et al. Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs. Aust Vet J. 2019 Sep 17. [Content Brief]
- [4]. Hassan AB, et al. Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers. Dtsch Tierarztl Wochenschr. 1990 Aug;97(8):315-7. [Content Brief]
- [5]. Iwata K, et al. Studies on the in vitro Antibacterial Activity of Leucomycin[J]. The Journal of Antibiotics, Series A, 1962, 15(6): 258-265.
- [6]. Kondo M, et al. Maridomycin, a new macrolide antibiotic. 3. In vitro and in vivo antibacterial activity. J Antibiot (Tokyo). 1973 Apr;26(4):206-14. [Content Brief]
- [7]. Liu G, et al. Quantitative analysis of impurities in leucomycin bulk drugs and tablets: A high performance liquid chromatography-charged aerosol detection method and its conversion to ultraviolet detection method. J Pharm Biomed Anal. 2021 Aug 5;202:114148. [Content Brief]
Keywords
