1395553-32-8
Chemical Structure
AS-1669058
- CAS No.: 1395553-32-8
- Formula:C20H17BrF2N4O5
- Molecular Weight:511.27
IUPAC Name: 3-(2-((2-(4-bromo-2,5-difluorophenyl)-6-methylpyrimidin-4-yl)amino)ethyl)pyridine 1-oxide oxalate
InChIKey: RHZMWZFMDCGRBP-UHFFFAOYSA-N
SMILES: CC1=CC(NCCC2=C[N+]([O-])=CC=C2)=NC(C3=CC(F)=C(Br)C=C3F)=N1.O=C(O)C(O)=O
Biological Activity: AS-1669058 is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 induces insulin secretion in response to high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 improved glucose tolerance and reduced blood glucose levels in db/db mice[1].
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AS-1669058 | AS-1669058 is a GPR119 agonist and a potential inhibitor of type 2 diabetes. AS-1669058 induces insulin secretion in response to high blood glucose levels in vitro and in vivo and increases insulin promoter activity. In animal studies, AS-1669058 improved glucose tolerance and reduced blood glucose levels in db/db mice. | |||||||||||||||||||||
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Keywords
