139755-91-2
139755-91-2
Chemical Structure
Desethyl sildenafil
Synonym(s): Sildenafil impurity C
- CAS No.: 139755-91-2
- Formula:C20H26N6O4S
- Molecular Weight:446.52
IUPAC Name: 5-(2-hydroxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
InChIKey: LTNJUPYNXDNXBO-UHFFFAOYSA-N
SMILES: O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC(S(=O)(N4CCN(C)CC4)=O)=CC=C3O)N1
Biological Activity: Desethyl Sildenafil (Sildenafil impurity C) is the impurity of Sildenafil (HY-15025). Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM[1].
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Desethyl sildenafil | Desethyl Sildenafil (Sildenafil impurity C) is the impurity of Sildenafil (HY-15025). Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM. | |||||||||||||||||||||
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Desethyl sildenafil-d3 | Desethyl Sildenafil-d3 is the deuterium labeled Desethyl Sildenafil. | |||||||||||||||||||||
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References
