1401998-36-4
1401998-36-4
Chemical Structure
Fimepinostat mesylate
Synonym(s): CUDC-907 mesylate
- CAS No.: 1401998-36-4
- Formula:C24H28N8O7S2
- Molecular Weight:604.66
InChIKey: CFLAKAHRZMPILU-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(N(CC2=CC3=NC(C4=CC=C(OC)N=C4)=NC(N5CCOCC5)=C3S2)C)N=C1)NO.CS(=O)(O)=O
Biological Activity: Fimepinostat mesylate potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with an IC50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively.
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Fimepinostat mesylate | Fimepinostat mesylate potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with an IC50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively. | |||||||||||||||||||||
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