1404073-10-4
Chemical Structure
NHS-Modified MMAF
- CAS. Nr.: 1404073-10-4
- Formula:C55H86N8O12
- Molecular Weight:1051.32
IUPAC Name: 2,5-dioxopyrrolidin-1-yl (3R,4S,7S,10S)-3-(2-((S)-2-((1R,2R)-3-(((S)-3-(1H-indol-3-yl)-1-(1,2-oxazinan-2-yl)-1-oxopropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-2-oxoethyl)-4-((S)-sec-butyl)-7,10-diisopropyl-5,11-dimethyl-6,9-dioxo-2-oxa-5,8,11-triazaheptadecan-17-oate
InChIKey: UTWYTYXLUHOUMT-AHDRROQBSA-N
SMILES: O=C(N1CCCCO1)[C@@H](NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O)CC4=CNC5=CC=CC=C45
Biological Activity: NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs)[1].
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NHS-Modified MMAF | NHS-Modified MMAF (WO2012143499A2, intermediat 210) is an intermediate which can be used for producing the anti-mesothelin binder-agent conjugates (ADCs). | |||||||||||||||||||||
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