1416313-72-8
1416313-72-8
Chemical Structure
Dynole 2−24
- CAS No.: 1416313-72-8
- Formula:C24H41N3
- Molecular Weight:371.60
IUPAC Name: N-((1-(3-(dimethylamino)propyl)-1H-indol-3-yl)methyl)decan-1-amine
InChIKey: ZXKCYZJGHXORKJ-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C=C(CNCCCCCCCCCC)C2=C1C=CC=C2
Biological Activity: Dynole 2−24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 μM for dynamin I). Dynole 2−24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM). Dynole 2−24 also shows 4.4-fold selectivity for dynamin I. Dynole 2−24 is active in-cell inhibitor of clathrin-mediated endocytosis[1]. CME: Clathrin mediated endocytosis
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Dynole 2−24 | 99.07% | Dynole 2−24 is an indole-based dynamin GTPase inhibitor (IC50=0.56 μM for dynamin I). Dynole 2−24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM). Dynole 2−24 also shows 4.4-fold selectivity for dynamin I. Dynole 2−24 is active in-cell inhibitor of clathrin-mediated endocytosis. CME: Clathrin mediated endocytosis | ||||||||||||||||||||
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