14166-26-8
14166-26-8
Chemical Structure
Taglutimide
Synonym(s): Biglumide; K 2004
- CAS No.: 14166-26-8
- Formula:C14H16N2O4
- Molecular Weight:276.29
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
InChIKey: URPJPYAYMWPUPR-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3C(C4CCC3C4)C2=O)=O)=O
Biological Activity: Taglutimide (Biglumide; K 2004) is an orally active hypnotic agent. Taglutimide lowers plasma levels of diphenhydramine in rats and shortens the duration of anesthesia. Taglutimide is used in research on neurological disorders such as sedation and hypnosis[1][2].
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Taglutimide | Taglutimide (Biglumide; K 2004) is an orally active hypnotic agent. Taglutimide lowers plasma levels of diphenhydramine in rats and shortens the duration of anesthesia. Taglutimide is used in research on neurological disorders such as sedation and hypnosis. | |||||||||||||||||||||
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References
- [1]. Jurecka W, et al. Teratologisch-neurotoxische Prüfung von Biglumid (K-2004) und Thalidomid [Teratologic-neurotoxicologic studies on biglumide (K-2004) and thalidomide]. Arch Toxicol. 1977 Jun 18;37(2):165-72. German. [Content Brief]
- [2]. Wiener H, et al. Induction of drug metabolism in the rat by taglutimide, a sedative-hypnotic glutarimide derivative. Eur J Drug Metab Pharmacokinet. 1980;5(2):93-7. [Content Brief]
