1416663-77-8

RO-5963 Chemical Structure
1416663-77-8

Chemical Structure

RO-5963

  • CAS No.: 1416663-77-8
  • Formula:C24H21ClF2N4O5
  • Molecular Weight:518.90

IUPAC Name: (E)-2-(4-((6-chloro-7-methyl-1H-indol-3-yl)methylene)-2,5-dioxoimidazolidin-1-yl)-2-(3,4-difluorophenyl)-N-(1,3-dihydroxypropan-2-yl)acetamide

InChIKey: ZFYQBPVMECJUBO-FBCYGCLPSA-N

SMILES: OCC(CO)NC(C(C1=CC(F)=C(F)C=C1)N2C(/C(NC2=O)=C\C(C3=CC=C4Cl)=CNC3=C4C)=O)=O

Biological Activity: RO-5963 is a dual p53-MDM2 and p53-MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-120086
RO-5963 98.19% RO-5963 is a dual p53-MDM2 and p53-MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively.
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