1421-14-3
1421-14-3
Chemical Structure
Propanidid
Synonym(s): Sombrevin; Fabantol
- CAS No.: 1421-14-3
- Formula:C18H27NO5
- Molecular Weight:337.41
IUPAC Name: propyl 2-(4-(2-(diethylamino)-2-oxoethoxy)-3-methoxyphenyl)acetate
InChIKey: KEJXLQUPYHWCNM-UHFFFAOYSA-N
SMILES: O=C(CC1=CC=C(C(OC)=C1)OCC(N(CC)CC)=O)OCCC
Biological Activity: Propanidid (Sombrevin; Fabantol) is a γ-aminobutyric acid type A (GABAA) receptor agonist and a short-acting non-barbiturate general agent that can suppress or relieve pain. Propanidid can decrease the arterial pressure[1][2].
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Propanidid | 98.19% | Propanidid (Sombrevin; Fabantol) is a γ-aminobutyric acid type A (GABAA) receptor agonist and a short-acting non-barbiturate general agent that can suppress or relieve pain. Propanidid can decrease the arterial pressure. | ||||||||||||||||||||
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References
- [1]. Cenani A, et al. In vitro and in vivo GABAA Receptor Interaction of the Propanidid Metabolite 4-(2-[Diethylamino]-2-Oxoethoxy)-3-Methoxy-Benzeneacetic Acid. Pharmacology. 2019;103(1-2):10-16. [Content Brief]
- [2]. Orko R. Anaesthesia for cardioversion: a comparison of diazepam, thiopentone and propanidid. Br J Anaesth. 1976 Mar;48(3):257-62. [Content Brief]
