1423715-30-3
Chemical Structure
LSD1-IN-51
- CAS No.: 1423715-30-3
- Formula:C16H16ClN3O4S
- Molecular Weight:381.83
IUPAC Name: (E)-3-(2-(1-(5-chloro-2-hydroxyphenyl)ethylidene)hydrazine-1-carbonyl)-N-methylbenzenesulfonamide
InChIKey: OKWHOGBLFYQHPU-VXLYETTFSA-N
SMILES: C(N/N=C(\C)/C1=C(O)C=CC(Cl)=C1)(=O)C2=CC(S(NC)(=O)=O)=CC=C2
Biological Activity: LSD1-IN-51 is a selective lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 value of 8.7 nM. LSD1-IN-51 selectively inhibits H3K4me1/2 demethylation by binding to the FAD domain of LSD1, while disrupting the interaction between LSD1 and multiprotein complexes such as HDAC1/2 and CoREST. LSD1-IN-51 can be used for cancer research[1].
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LSD1-IN-51 | LSD1-IN-51 is a selective lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 value of 8.7 nM. LSD1-IN-51 selectively inhibits H3K4me1/2 demethylation by binding to the FAD domain of LSD1, while disrupting the interaction between LSD1 and multiprotein complexes such as HDAC1/2 and CoREST. LSD1-IN-51 can be used for cancer research. | |||||||||||||||||||||
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