1426173-48-9
Chemical Structure
Cefprozil-d4
- CAS No.: 1426173-48-9
- Formula:C18H15D4N3O5S
- Molecular Weight:393.45
IUPAC Name: (6R,7R)-7-((R)-2-amino-2-(4-hydroxyphenyl-2,3,5,6-d4)acetamido)-8-oxo-3-((E)-prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: WDLWHQDACQUCJR-BMKVJPEASA-N
SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](N)C3=C(C(=C(O)C(=C3[2H])[2H])[2H])[2H])=O)C2=O)(SCC1/C=C/C)[H]
Biological Activity: Cefprozil-d4 is the deuterium labeled Cefprozi (HY-B0458A)[1]. Cefprozil is a second-generation cephalosporin type antibiotic. Cefprozil exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections[2][3].
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Cefprozil-d4 | Cefprozil-d4 is the deuterium labeled Cefprozi (HY-B0458A). Cefprozil is a second-generation cephalosporin type antibiotic. Cefprozil exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. | |||||||||||||||||||||
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Cefprozil | Cefprozil is a second-generation cephalosporin type antibiotic. Cefprozil exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections. | |||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. J C Fung-Tom, et al. Antibacterial activities of cefprozil compared with those of 13 oral cephems and 3 macrolides. Antimicrob Agents Chemother. 1995 Feb;39(2):533-8. [Content Brief]
- [3]. Wiseman LR, et al., Cefprozil. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic potential. Drugs. 1993 Feb;45(2):295-317. [Content Brief]
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