1426576-80-8
1426576-80-8
Chemical Structure
ML243
- CAS No.: 1426576-80-8
- Formula:C14H16N2OS
- Molecular Weight:260.35
IUPAC Name: (E)-N-(4,5-dihydrothiazol-2-yl)-3-(4-ethylphenyl)acrylamide
InChIKey: MTLJBAFNMHPGBV-BQYQJAHWSA-N
SMILES: CCC1=CC=C(/C=C/C(NC2=NCCS2)=O)C=C1
Biological Activity: ML243 is a selective small-molecule inhibitor of breast cancer stem cells. ML243 has 32-fold greater selective inhibition in the breast CSC-like cell line HMLE_shECad than the control cell line HMLE_shGFP. ML243 may target the Wnt pathway at the protein level without altering RNA expression levels[1].
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ML243 | ML243 is a selective small-molecule inhibitor of breast cancer stem cells. ML243 has 32-fold greater selective inhibition in the breast CSC-like cell line HMLE_shECad than the control cell line HMLE_shGFP. ML243 may target the Wnt pathway at the protein level without altering RNA expression levels. | |||||||||||||||||||||
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