1429024-58-7
1429024-58-7
Chemical Structure
STL1267
- CAS No.: 1429024-58-7
- Formula:C17H11ClN4O
- Molecular Weight:322.75
IUPAC Name: 6-([1,1'-biphenyl]-2-yloxy)-3-chloro-[1,2,4]triazolo[4,3-b]pyridazine
InChIKey: XWHTYUYQMHCFMT-UHFFFAOYSA-N
SMILES: ClC1=NN=C2C=CC(OC3=C(C4=CC=CC=C4)C=CC=C3)=NN12
Biological Activity: STL1267 is a potent and cross-the-blood-brain barrier REV-ERB agonist with a Ki value of 0.16 µM for REV-ERBα. STL1267 shows no cytotoxicity. STL1267 inhibits the gene expression of BMAL1[1].
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STL1267 | 99.83% | STL1267 is a potent and cross-the-blood-brain barrier REV-ERB agonist with a Ki value of 0.16 µM for REV-ERBα. STL1267 shows no cytotoxicity. STL1267 inhibits the gene expression of BMAL1. | ||||||||||||||||||||
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References
Keywords
