143-27-1
Chemical Structure
Cetylamine
Synonym(s): Hexadecylamine
- CAS No.: 143-27-1
- Formula:C16H35N
- Molecular Weight:241.46
IUPAC Name: hexadecan-1-amine
InChIKey: FJLUATLTXUNBOT-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCCN
Biological Activity: Cetylamine (Hexadecylamine) is an amphipathic hexadecyl alkylamine. Cetylamine enhances phase separation of aqueous PVA solutions, promotes the formation of PVA crystalline domains while remaining amorphous itself, and enables the preparation of surfactant-free, solvent-free, and crosslinker-free PVA hydrogels via freeze-thaw blending. Cetylamine can serve as the cationic surfactant component in ion-crosslinked micelles, which can load hydrophobic drugs and deliver them to breast cancer cells. Cetylamine is applicable to breast cancer-related research[1][2].
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Cetylamine | 98.0% | Cetylamine (Hexadecylamine) is an amphipathic hexadecyl alkylamine. Cetylamine enhances phase separation of aqueous PVA solutions, promotes the formation of PVA crystalline domains while remaining amorphous itself, and enables the preparation of surfactant-free, solvent-free, and crosslinker-free PVA hydrogels via freeze-thaw blending. Cetylamine can serve as the cationic surfactant component in ion-crosslinked micelles, which can load hydrophobic drugs and deliver them to breast cancer cells. Cetylamine is applicable to breast cancer-related research. | ||||||||||||||||||||
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- [1]. Alvear-Jiménez A, et al. Hexadecylamine Addition Promotes Crystallization-Driven Functionalities in Freezing-Thaw PVA Hydrogels. Macromolecules. 2025 Dec 09;58(23):12564-12573.
- [2]. Alkhafaji E, et al. Preparation of novel shell-ionotropically crosslinked micelles based on hexadecylamine and tripolyphosphate for cancer drug delivery. Pharmaceutical development and technology. 2024 Apr;29(4):322-338.
Keywords