143413-85-8
Chemical Structure
Thiazole orange dimer YOYO 1
Synonym(s): YOYO 1; YOYO1
- CAS No.: 143413-85-8
- Formula:C49H58I4N6O2
- Molecular Weight:1270.64
IUPAC Name: 1,1'-((propane-1,3-diylbis(dimethylammoniumdiyl))bis(propane-3,1-diyl))bis(4-((Z)-(3-methylbenzo[d]oxazol-2(3H)-ylidene)methyl)quinolin-1-ium) iodide
InChIKey: GRRMZXFOOGQMFA-UHFFFAOYSA-J
SMILES: CN1C2=CC=CC=C2O/C1=C\C3=CC=[N+](C4=C3C=CC=C4)CCC[N+](CCC[N+](CCC[N+]5=CC=C(C6=C5C=CC=C6)/C=C7N(C8=C(O/7)C=CC=C8)C)(C)C)(C)C.[I-].[I-].[I-].[I-]
Biological Activity: Thiazole orange dimer YOYO 1 (YOYO 1) is a cell-impermeable cyanine dimer with no inherent fluorescence, and its fluorescence intensity increases significantly upon binding to double-stranded DNA (dsDNA). Thiazole orange dimer YOYO 1 can serve as a nuclear counterstain or a dead cell indicator (Ex/Em = 505/512 nm).
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Thiazole orange dimer YOYO 1 | Thiazole orange dimer YOYO 1 (YOYO 1) is a cell-impermeable cyanine dimer with no inherent fluorescence, and its fluorescence intensity increases significantly upon binding to double-stranded DNA (dsDNA). Thiazole orange dimer YOYO 1 can serve as a nuclear counterstain or a dead cell indicator (Ex/Em = 505/512 nm). | |||||||||||||||||||||
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