143413-86-9
143413-86-9
Chemical Structure
Oxazole yellow
- CAS No.: 143413-86-9
- Formula:C19H17IN2O
- Molecular Weight:416.26
IUPAC Name: (Z)-1-methyl-4-((3-methylbenzo[d]oxazol-2(3H)-ylidene)methyl)quinolin-1-ium iodide
InChIKey: YBTNFTNPBCSMSD-UHFFFAOYSA-M
SMILES: C[N+](C1=C2C=CC=C1)=CC=C2/C=C3N(C)C4=C(C=CC=C4)O/3.[I-]
Biological Activity: Oxazole yellow is a cyanine dye composed of benzoxazole and quinoline rings connected by a linker. It is almost non-luminescent in water, but its green fluorescence is significantly enhanced after intercalation in double-stranded DNA. Oxazole yellow can be used to detect cell apoptosis[1][2][3].
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Oxazole yellow | Oxazole yellow is a cyanine dye composed of benzoxazole and quinoline rings connected by a linker. It is almost non-luminescent in water, but its green fluorescence is significantly enhanced after intercalation in double-stranded DNA. Oxazole yellow can be used to detect cell apoptosis. | |||||||||||||||||||||
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References
- [1]. Jin C, et al. Molecular Dynamics of Oxazole Yellow Dye in its Ground and First Excited Electronic States in Solution and when Intercalated in dsDNA[J]. The Journal of Physical Chemistry B, 2017, 121(44): 10242-10248. [Content Brief]
- [2]. Zhu H, et al. High-sensitivity capillary electrophoresis of double-stranded DNA fragments using monomeric and dimeric fluorescent intercalating dyes[J]. Analytical chemistry, 1994, 66(13): 1941-1948. [Content Brief]
- [3]. Eriksson M, et al. Binding of intercalating and groove-binding cyanine dyes to bacteriophage T5[J]. The journal of physical chemistry B, 2007, 111(5): 1139-1148. [Content Brief]
