1435727-97-1
Chemical Structure
Duloxetine-d3 hydrochloride
Synonym(s): (S)-Duloxetine D3 hydrochloride; LY248686 D3 hydrochloride
- CAS No.: 1435727-97-1
- Formula:C18H17D3ClNOS
- Molecular Weight:336.89
IUPAC Name: (S)-N-(methyl-d3)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride
InChIKey: BFFSMCNJSOPUAY-HQKLNPQUSA-N
SMILES: [2H]C([2H])([2H])NCC[C@H](OC1=CC=CC2=C1C=CC=C2)C3=CC=CS3.[H]Cl
Biological Activity: Duloxetine-d3 (hydrochloride) is a deuterium labeled Duloxetine hydrochloride. Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2].
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Duloxetine-d3 hydrochloride | Duloxetine-d3 (hydrochloride) is a deuterium labeled Duloxetine hydrochloride. Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | |||||||||||||||||||||
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Duloxetine hydrochloride (Standard) | ≥98% | Duloxetine (hydrochloride) (Standard) is the analytical standard of Duloxetine (hydrochloride). This product is intended for research and analytical applications. Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | ||||||||||||||||||||
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Duloxetine-d7 hydrochloride | Duloxetine-d7 hydrochloride ((S)-Duloxetine-d7 hydrochloride) is the deuterium labeled Duloxetine hydrochloride (HY-B0161A). Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | |||||||||||||||||||||
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Duloxetine hydrochloride | 99.97% | Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | ||||||||||||||||||||
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References
- [1]. De Berardis, D., et al., The effect of newer serotonin-noradrenalin antidepressants on cytokine production: a review of the current literature. Int J Immunopathol Pharmacol, 2010. 23(2): p. 417-22. [Content Brief]
- [2]. Wang, S.Y., J. Calderon, and G. Kuo Wang, Block of neuronal Na+ channels by antidepressant duloxetine in a state-dependent manner. Anesthesiology, 2010. 113(3): p. 655-65. [Content Brief]
