1443553-08-9
Chemical Structure
ATTO 488 carboxylic acid
- CAS No.: 1443553-08-9
- Formula:C25H23N3O10S2
- Molecular Weight:589.59
IUPAC Name: 3,6-diamino-9-(2-((3-carboxypropyl)(methyl)carbamoyl)phenyl)-5-sulfoxanthylium-4-sulfonate
InChIKey: PNCUNWSKHFBORG-UHFFFAOYSA-N
SMILES: O=C(CCCN(C)C(C1=C(C2=C(C=CC(N)=C3S(=O)(O)=O)C3=[O+]C4=C2C=CC(N)=C4S(=O)([O-])=O)C=CC=C1)=O)O
Biological Activity: ATTO 488 carboxylic acid is a bright green fluorescent dye with high photostability, which is commonly used in protein fluorescent labeling, single-molecule fluorescence imaging and super-resolution microscopy studies. The carboxylic acid form of ATTO 488 can be covalently coupled to primary amines of proteins via activation, or prepared into a maleimide derivative for coupling with thiol groups; it emits green fluorescence after labeling. Ex/Em = 488/524 nm[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ATTO 488 carboxylic acid | 97.24% | ATTO 488 carboxylic acid is a bright green fluorescent dye with high photostability, which is commonly used in protein fluorescent labeling, single-molecule fluorescence imaging and super-resolution microscopy studies. The carboxylic acid form of ATTO 488 can be covalently coupled to primary amines of proteins via activation, or prepared into a maleimide derivative for coupling with thiol groups; it emits green fluorescence after labeling. Ex/Em = 488/524 nm. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Akkilic N, et al. Monitoring the Switching of Single BSA-ATTO 488 Molecules Covalently End-Attached to a pH-Responsive PAA Brush. Langmuir : the ACS journal of surfaces and colloids. 2016 Sep 06;32(35):8803-11.
- [2]. Zhang Z, et al. Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment. Biochimica et biophysica acta. Biomembranes. 2017 Jul;1859(7):1242-1253.
- [3]. Han Y, et al. Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions. Nature communications. 2017 Nov 03;8(1):1307. [Content Brief]
