144397-99-9
144397-99-9
Chemical Structure
Obscurolide A1
- CAS No.: 144397-99-9
- Formula:C15H17NO5
- Molecular Weight:291.30
IUPAC Name: (E)-4-((2-(3-hydroxybut-1-en-1-yl)-5-oxotetrahydrofuran-3-yl)amino)benzoic acid
InChIKey: IZSWILLJDXDGDJ-FARCUNLSSA-N
SMILES: O=C(C1=CC=C(C=C1)NC(C(O2)/C=C/C(C)O)CC2=O)O
Biological Activity: Obscurolide A1 is a Phosphodiesterase (PDE) inhibitor (IC50=8 mM) that can be obtained from Streptomyces viridochromogenes culture. Obscurolide A1 has the potential to study neurological and inflammatory diseases[1].
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Obscurolide A1 | Obscurolide A1 is a Phosphodiesterase (PDE) inhibitor (IC50=8 mM) that can be obtained from Streptomyces viridochromogenes culture. Obscurolide A1 has the potential to study neurological and inflammatory diseases. | |||||||||||||||||||||
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References
- [1]. Hoff H, et al. Metabolic products of microorganisms. 261. Obscurolides, a novel class of phosphodiesterase inhibitors from streptomyces. I. Production, isolation, structural elucidation and biological activity of obscurolides A1 to A4. J Antibiot (Tokyo). 1992 Jul;45(7):1096-107. [Content Brief]
