1446501-77-4
1446501-77-4
Chemical Structure
AGI-12026
Synonym(s): AGI-026
- CAS No.: 1446501-77-4
- Formula:C18H15F6N7
- Molecular Weight:443.35
IUPAC Name: N2-isopropyl-6-(6-(trifluoromethyl)pyridin-2-yl)-N4-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazine-2,4-diamine
InChIKey: DWIQMUBNZXFUDC-UHFFFAOYSA-N
SMILES: FC(F)(F)C1=CC=CC(C2=NC(NC(C)C)=NC(NC3=CC(C(F)(F)F)=NC=C3)=N2)=N1
Biological Activity: AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma[1].
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AGI-12026 | AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma. | |||||||||||||||||||||
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