144674-89-5

U 89674 Chemical Structure
144674-89-5

Chemical Structure

U 89674

  • CAS No.: 144674-89-5
  • Formula:C24H31N7O
  • Molecular Weight:433.56

IUPAC Name: (E)-N'-(2-(4-(3-(isopropylamino)pyridin-2-yl)piperazine-1-carbonyl)-1H-indol-5-yl)-N,N-dimethylformimidamide

InChIKey: MQLULHDHQQQZQU-WGOQTCKBSA-N

SMILES: O=C(C1=CC=2C=C(N=CN(C)C)C=CC2N1)N3CCN(C4=NC=CC=C4NC(C)C)CC3

Biological Activity: U 89674 is a nonnucleoside HIV-1 reverse transcriptase inhibitor with no cytotoxic effect on cells at concentrations of 10 μM or lower over 7 days. U 89674 modulates reverse transcriptase activity, interfering with HIV-1 replication. U 89674 inhibits replication of HIV-1 laboratory strains and primary HIV-1 isolates in immune cells. U 89674 delays virus-induced cell killing in mixed cultures of uninfected and HIV-1-infected cells. U 89674 can be used for the research of HIV-1 infection[1].

Cat. No. Product Name Purity Description Pricing
HY-187598
U 89674 U 89674 is a nonnucleoside HIV-1 reverse transcriptase inhibitor with no cytotoxic effect on cells at concentrations of 10 μM or lower over 7 days. U 89674 modulates reverse transcriptase activity, interfering with HIV-1 replication. U 89674 inhibits replication of HIV-1 laboratory strains and primary HIV-1 isolates in immune cells. U 89674 delays virus-induced cell killing in mixed cultures of uninfected and HIV-1-infected cells. U 89674 can be used for the research of HIV-1 infection.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References