1448711-61-2
1448711-61-2
Chemical Structure
PI3Kα-IN-16
- CAS No.: 1448711-61-2
- Formula:C27H24N2O2
- Molecular Weight:408.49
InChIKey: CCPVJNGJNZLMDG-UHFFFAOYSA-N
SMILES: CCN1C2=CC=CC=C2C3=C1C(C4=CC=CC5=C4C=CC=C5)=NC(C(OC(C)C)=O)=C3
Biological Activity: PI3Kα-IN-16 (Z86) is a novel PI3Kα inhibitor with an IC50 value of 4.28 μM. PI3Kα-IN-16 has potent inhibitory efficiency on PI3K-mediated CRCs growth and migration. PI3Kα-IN-16 also inhibits the Wnt signaling pathway[1].
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PI3Kα-IN-16 | PI3Kα-IN-16 (Z86) is a novel PI3Kα inhibitor with an IC50 value of 4.28 μM. PI3Kα-IN-16 has potent inhibitory efficiency on PI3K-mediated CRCs growth and migration. PI3Kα-IN-16 also inhibits the Wnt signaling pathway. | |||||||||||||||||||||
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