1449473-97-5

PF-06305591 Chemical Structure
1449473-97-5

Chemical Structure

PF-06305591

  • CAS No.: 1449473-97-5
  • Formula:C15H22N4O
  • Molecular Weight:274.36

IUPAC Name: (2R,3S)-3-amino-3-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)-2-methylpropanamide

InChIKey: APWZIFIAVVFPNT-PELKAZGASA-N

SMILES: CC(C)(C)C1=CC=C(NC([C@H]([C@@H](C)C(N)=O)N)=N2)C2=C1

Biological Activity: PF-06305591 is a potent and highly selective voltage gated sodium channel NaV1.8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile[1].

Cat. No. Product Name Purity Description Pricing
HY-114301 		PF-06305591 99.74% PF-06305591 is a potent and highly selective voltage gated sodium channel NaV1.8 blocker, with an IC50 of 15 nM. An excellent preclinical in vitro ADME and safety profile.
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