1453082-52-4

NVP-CLR457 Chemical Structure
1453082-52-4

Chemical Structure

NVP-CLR457

  • CAS No.: 1453082-52-4
  • Formula:C18H20F3N7O4
  • Molecular Weight:455.39

IUPAC Name: (4S,5R)-3-(2'-amino-2-morpholino-4'-(trifluoromethyl)-[4,5'-bipyrimidin]-6-yl)-4-(hydroxymethyl)-5-methyloxazolidin-2-one

InChIKey: IEYOHYVYEJVEJJ-SKDRFNHKSA-N

SMILES: NC1=NC(C(F)(F)F)=C(C2=NC(N3CCOCC3)=NC(N4[C@H]([C@H](OC4=O)C)CO)=C2)C=N1

Biological Activity: NVP-CLR457 (compound 40) is an orally active, potent and balanced pan-class I PI3K inhibitor. NVP-CLR457 shows a clear dose-dependent PK/PD/efficacy relationship. NVP-CLR457 has antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-146260
NVP-CLR457 NVP-CLR457 (compound 40) is an orally active, potent and balanced pan-class I PI3K inhibitor. NVP-CLR457 shows a clear dose-dependent PK/PD/efficacy relationship. NVP-CLR457 has antitumor activity.
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