1454588-34-1
Chemical Structure
Protease-Activated Receptor-1 antagonist 2
- CAS No.: 1454588-34-1
- Formula:C24H23F2N3O2
- Molecular Weight:423.46
IUPAC Name: 2-(6-((E)-2-((3R,3aS,4R,5S,7aS)-7a-amino-6,6-difluoro-3,5-dimethyl-1-oxooctahydroisobenzofuran-4-yl)vinyl)pyridin-3-yl)benzonitrile
InChIKey: QSPXDRZNKJEHEU-KJQHQIRPSA-N
SMILES: [H][C@]12[C@H]([C@@H](C(F)(C[C@]1(C(O[C@@H]2C)=O)N)F)C)/C=C/C3=CC=C(C=N3)C4=CC=CC=C4C#N
Biological Activity: Protease-Activated Receptor-1 antagonist 2 is an orally active protease-activated receptor-1 (PAR-1) antagonist, with an IC50 value of 7 nM. Protease-Activated Receptor-1 antagonist 2 has favorable pharmacokinetic properties which is useful in the research of cardiovascular disease (CVD), such as atherosclerosis and restenosis[1].
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Protease-Activated Receptor-1 antagonist 2 | Protease-Activated Receptor-1 antagonist 2 is an orally active protease-activated receptor-1 (PAR-1) antagonist, with an IC50 value of 7 nM. Protease-Activated Receptor-1 antagonist 2 has favorable pharmacokinetic properties which is useful in the research of cardiovascular disease (CVD), such as atherosclerosis and restenosis. | |||||||||||||||||||||
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