1454651-67-2

EGFR-IN-180 Chemical Structure
1454651-67-2

Chemical Structure

EGFR-IN-180

  • CAS No.: 1454651-67-2
  • Formula:C30H38ClN7O3
  • Molecular Weight:580.12

InChIKey: BCSHRERPHLTPEE-UHFFFAOYSA-N

SMILES: O=C(C1=C(NC2=NC(NC3=CC=C4C(CCCC(C4)N5CCN(CC5)CCO)=C3OC)=NC=C2Cl)C=CC=C1)NC

Biological Activity: EGFR-IN-180 (Compound L15) is an EGFR inhibitor. EGFR-IN-180 shows inhibitory activity against EFGR and EGFR harboring the L858R/T790M/C797S triple drug-resistant mutation, with IC50 values of 80.96 nM and 16.43 nM, reapectively. EGFR-IN-180 can be used for the study of non-small cell lung cancer (NSCLC)[1].

Cat. No. Product Name Purity Description Pricing
HY-178824 		EGFR-IN-180 EGFR-IN-180 (Compound L15) is an EGFR inhibitor. EGFR-IN-180 shows inhibitory activity against EFGR and EGFR harboring the L858R/T790M/C797S triple drug-resistant mutation, with IC50 values of 80.96 nM and 16.43 nM, reapectively. EGFR-IN-180 can be used for the study of non-small cell lung cancer (NSCLC).
Pricing 
Expand Hide
loading...
/
  • /
loading...
Size Price
Stock Quantity Availability Operate
/
In-stock
(Estimated to ship on )
(Estimated to ship TODAY)
Estimated to ship on
(Estimated to ship TODAY)
Amount: USD 0.00

This product is a controlled substance and not for sale in your territory.
Pricing 
Expand Hide
References

Keywords