EGFR-IN-180
EGFR-IN-180 (Compound L15) is an EGFR inhibitor. EGFR-IN-180 shows inhibitory activity against EFGR and EGFR harboring the L858R/T790M/C797S triple drug-resistant mutation, with IC50 values of 80.96 nM and 16.43 nM, reapectively. EGFR-IN-180 can be used for the study of non-small cell lung cancer (NSCLC).
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- No. CAS: 1454651-67-2
- Fòrmula: C30H38ClN7O3
- Peso molecular:580.12
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 1454651-67-2
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Peso molecular 580.12
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Fòrmula C30H38ClN7O3
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SMILES
O=C(C1=C(NC2=NC(NC3=CC=C4C(CCCC(C4)N5CCN(CC5)CCO)=C3OC)=NC=C2Cl)C=CC=C1)NC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)