EGFR-IN-180
EGFR-IN-180 (Compound L15) is an EGFR inhibitor. EGFR-IN-180 shows inhibitory activity against EFGR and EGFR harboring the L858R/T790M/C797S triple drug-resistant mutation, with IC50 values of 80.96 nM and 16.43 nM, reapectively. EGFR-IN-180 can be used for the study of non-small cell lung cancer (NSCLC).
For research use only. We do not sell to patients.
- CAS No.: 1454651-67-2
- Formula: C30H38ClN7O3
- Molecular Weight:580.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Chemical Information
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CAS No. 1454651-67-2
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Molecular Weight 580.12
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Formula C30H38ClN7O3
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SMILES
O=C(C1=C(NC2=NC(NC3=CC=C4C(CCCC(C4)N5CCN(CC5)CCO)=C3OC)=NC=C2Cl)C=CC=C1)NC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)