14686-61-4
14686-61-4
Chemical Structure
N-Formyldemecolcine
- CAS. Nr.: 14686-61-4
- Formula:C22H25NO6
- Molecular Weight:399.44
InChIKey: HTWMEJLBEVTMMZ-INIZCTEOSA-N
SMILES: COC1=C2C(C([C@H](CCC2=CC(OC)=C1OC)N(C)C=O)=C3)=CC=C(OC)C3=O
Biological Activity: N-Formyldemecolcine is a colchicine precursor that contains the characteristic tropolone ring and pharmacophore of colchicine. N-Formyldemecolcine can be synthesized de novo by genetically engineering transgenic Nicotiana benthamiana and atypical cytochrome P450s that catalyze the production of colchicine's unique carbon scaffold[1].
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N-Formyldemecolcine | N-Formyldemecolcine is a colchicine precursor that contains the characteristic tropolone ring and pharmacophore of colchicine. N-Formyldemecolcine can be synthesized de novo by genetically engineering transgenic Nicotiana benthamiana and atypical cytochrome P450s that catalyze the production of colchicine's unique carbon scaffold. | |||||||||||||||||||||
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