148717-47-9
Chemical Structure
NPS-467
- CAS No.: 148717-47-9
- Formula:C18H23NO
- Molecular Weight:269.38
InChIKey: WOPAHKKTEVUGOE-UHFFFAOYSA-N
SMILES: CC(NCCCC1=CC=CC=C1)C2=CC(OC)=CC=C2
Biological Activity: NPS-467 is a calcium-sensing receptor (CaR) activator and stereospecific agent with only its R-enantiomer active. NPS-467 increases the sensitivity of the CaR to activation by extracellular calcium. NPS-467 stimulates stanniocalcin (STC) secretion in trout and induces inhibition of gill calcium transport in trout. NPS-467 has no effect on serum calcitonin levels in trout[1].
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NPS-467 | NPS-467 is a calcium-sensing receptor (CaR) activator and stereospecific agent with only its R-enantiomer active. NPS-467 increases the sensitivity of the CaR to activation by extracellular calcium. NPS-467 stimulates stanniocalcin (STC) secretion in trout and induces inhibition of gill calcium transport in trout. NPS-467 has no effect on serum calcitonin levels in trout. | |||||||||||||||||||||
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Keywords